Clarence Clemons, the burly star saxophonist of Bruce Springsteen's E Street band, died Saturday, six days after suffering a stroke following surgery. Clemons was 69.

His bandleader, Springsteen, said on his website Clemons' loss is “immeasurable.” Springsteen said “we are honored and thankful to have know him and had the opportunity to stand beside him for nearly 40 years.”

Clemons died at his home in Florida. His health was fragile in recent years after undergoing hip and knee surgeries.

Clemons' powerful raw style was featured on many hits by Springsteen, including “Born to Run” and “Jungleland.”

Clemons last appeared with Springsteen and his longtime band in December.

Clemons is the second E Street Band member to die. Longtime keyboard player Danny Federici died of cancer nearly three years ago at the age of 58.